Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 33.00 | |
100 mg | In stock | $ 47.00 | |
200 mg | In stock | $ 68.00 | |
500 mg | In stock | $ 112.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE. |
In vitro | Clofibric acid enhances the expression of carbonyl reductase in vivo, reduces PGE2 levels, and diminishes the quantity of vascular endothelial growth factor (VEGF) in OVCAR-3 tumors and DISS-origin ascites. In solid OVCAR-3 tumors, it decreases microvascular density and induces apoptosis. Compared to the control, a 9,000 ppm Clofibric acid diet significantly reduces the growth of OVCAR-3 tumor xenografts s.c. by 46% and notably prolongs the survival of mice with DISS-origin malignant ascites. |
In vivo | Clofibric acid enhances the expression of the CYP4A6 gene in RK13 cells transfected with PPAR-Gamma. |
Synonyms | Chlorofibrinic acid |
Molecular Weight | 214.65 |
Formula | C10H11ClO3 |
CAS No. | 882-09-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 40 mg/mL (186.3 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 40 mg/mL (186.3 mM)
You can also refer to dose conversion for different animals. More
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Clofibric acid 882-09-7 DNA Damage/DNA Repair Metabolism PPAR Drug Metabolite Peroxisome proliferator-activated receptors Chlorofibrinic acid Inhibitor inhibit inhibitor